Liverpool striker Luis Suarez will be suspended for ten matches from immediate effect after the club decided against appealing the decision.
The ban was handed to the Uruguayan after he bit Chelsea defender Branislav Ivanovic in the 2-2 draw at Anfield on Sunday.
The Football Association confirmed that Liverpool, who had a deadline of midday today to contest the decision, made no such approach.
This means the clubs top scorer will miss the remainder of this season, and the opening weeks of the 2013/14 campaign.
The Reds will begin the run of games without their star player at St. James Park, where they will face a Newcastle United side looking for three points that will all but secure their Premier League status.
Daniel Sturridge will lead the line for the Reds, while Fabio Borini could feature having missed the majority of the season with a dislocated shoulder.
Martin Kelly and Joe Allen are out until next season, while Raheem Sterling also remains side-lined.
It was of course Suarez who scored the equaliser with one of the goals of the season in the 1-1 draw at Anfield when the sides met in November, after Yohan Cabaye had given Newcastle a first half lead.